Cortexyme Announces Partnership with Parkinson Study Group and Upcoming Alzheimer’s Disease Data Presentation
-- Partnership with
-- Presentation at AD/PD™ 2021 Underscores Relevance of Cortexyme’s Approach --
Along with Fernandez, the new
Patrik Brundin, M.D., Ph.D., Honorary Guest to the PSG
Eric Macklin, Ph.D., PSG Executive Committee Member
Zoltan Mari, M.D., Co-Chair of the PSG Motor Features of PD Working Group
Andrew Siderowf, M.D., PSG Executive Committee Member
“Our partnership with the PSG demonstrates the importance of Cortexyme’s evidence to date and the potential to benefit patients suffering from Parkinson’s disease,” said
Mounting evidence supports the role of P. gingivalis in Parkinson’s disease, including research supporting the epidemiological link between periodontal disease and Parkinson’s disease and rodent studies demonstrating that oral P. gingivalis infection causes alpha-synuclein production and degeneration of dopamine-producing neurons in the substantia nigra of the brain. For further details, visit www.cortexyme.com/science.
AD/PD 2021 Presentation Furthers Link Between P. gingivalis and Neurodegeneration
In the poster, scientists at the
“This research adds to the growing body of evidence that shows the presence of gingipains in the human AD brain and the validation of new electron microscopy techniques that can be leveraged for future research into sub-cellular localization of gingipains within neurons and astrocytes,” said
View the abstract “Ultrastructural localization of Porphyromonas gingivalis RgpB virulence factor in the middle temporal gyrus (MTG) of the Alzheimer’s disease human brain” here on Cortexyme’s website following the conference.
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